Gambaran Kadar Sgot dan Sgpt pada Pasien Tuberkulosis Paru Aktif

Main Article Content

Graciela Stephanie
Maulida Julia Saputri
Suparno Putera Makkadafi

Abstract

Tuberculosis (TB) is a global problem with around half a percent of the world's population infected. The number of TB cases in Samarinda City in 2021 will reach 1,464 cases. TB treatment can damage the liver, and the SGOT and SGPT enzymes are related to liver function. SGPT is more commonly found in the liver, while SGOT is found in the liver, heart, skeletal muscles, kidneys, brain and blood cells. The purpose of this study was to determine the levels of SGOT and SGPT in patients with active pulmonary tuberculosis at the Sidomulyo Health Center in Samarinda. This type of research is a descriptive observational study with 30 samples of pulmonary TB patients who are currently undergoing anti-tuberculosis drug (OAT) treatment. Sampling was carried out using total sampling technique. The variables observed were SGOT and SGPT levels. The results of measurements using spectrophotometry showed that normal AST levels were mostly found in 100% female patients, while abnormal AST levels were mostly found in male patients (53%). The highest normal SGPT levels were found in male patients (100%), while the highest abnormal SGPT levels were found in female patients (27%). The examination results also showed that the adult age group with an age range of 20-59 years had normal SGOT levels (33%) and high normal SGPT levels (96%). It can be concluded that the results of SGOT levels based on sex are abnormal in male patients, whereas based on age the results of abnormal SGOT levels in adult patients. Furthermore, SGPT levels based on sex were abnormal in female patients while based on age SGPT levels were abnormal in adolescent patients.

Article Details

How to Cite
Stephanie, G., Maulida Julia Saputri , M. J. S. ., & Suparno Putera Makkadafi , S. P. M. . (2024). Gambaran Kadar Sgot dan Sgpt pada Pasien Tuberkulosis Paru Aktif. Jurnal Sains Dan Kesehatan, 3(1), 22–27. https://doi.org/10.57151/jsika.v3i1.261
Section
Articles

References

Ardiani, T., & Azmi, R. N. (2021). Identifikasi Kejadian Hepatotoksik pada Pasien Tuberkulosis dengan Penggunaan Obat Anti Tuberkulosis di Rumah Sakit Umum Daerah Abdul Wahab Sjahranie. Borneo Student Research, 3(1), 978–985.

Hasni, Syarif, J., & Darwis, I. (2018). Gambaran Hasil Pemeriksaan Sgot Dan Sgpt Pada Penghirup Lem Di Jalan Abdul Kadir Kota Makassar. Jurnal Media Laboran, 8(2), 43–49.

Juliarta, I. G., Mulyantari, N. K., & Yasa, I. wayan P. S. (2018). Gambaran hepatotoksisitas ( ALT / AST ) penggunaan obat antituberkulosis lini pertama dalam pengobatan pasien tuberkulosis paru rawat inap di RSUP Sanglah Denpasar tahun 2014. E-Jurnal Medika, 7(10), 1–10.

Kristini, T., & Hamidah, R. (2020). Potensi Penularan Tuberculosis Paru pada Anggota Keluarga Penderita. Jurnal Kesehatan Masyarakat Indonesia, 15(1), 24.https://doi.org/10.26714/jkmi.15.1.2020.24-28

Muhamad Nizar, SKM., M. M. E. (2017). Buku Pemberantasan dan Penanggulangan Tuberkulosis.pdf. Gosyen Publishing.

Muslim, A. S. (2020). Program Intervensi Dalam Upaya Penurunan Kasus Baru Tuberkulosis Paru Di Wilayah Kerja Puskesmas Teluknaga. Jurnal Bagus, 02(01), 402–406.

Provinsi, D. (2020). Profil Kesehatan Tahun 2020. DinkesProvKaltim, 57.

Putri, T. M. (2021). Total SGOT, SGPT and Bilirubin Levels in Pulmonary Tuberculosis Patients.

Jaringan Laboratorium Medis, 3(1), 13–23. https://doi.org/10.31983/jlm.v3i1.7917

Reza, & Rachmawati. (2017). Perbedaan Kdar SGOT dan SGPT Antara Subyek Dengan Dan Tanpa Diabetes Mellitus. Kedokteran, 6(2), 158–166.

Sidabutar, N. E. (2020). Gambaran Kadar SGOT dan SGPT Pada Penderita Tuberkulosis Paru Di Rumah Sakit Umum Daerah Tarutung. Kaos GL Dergisi, 8(75), 147–154.

Safithri, Fathiyah. (2018) ‘Diagnosis TB Dewasa dan Anak Berdasarkan ISTC (International Srandard for TB Care)’, Saintika Medika, 7(2). doi: 10.22219/sm.v7i2.4078.

Sari, Ida Diana., Yuniar, Yuni. and Syaripuddin, Muhammad. (2017) ‘Studi Monitoring Efek Samping Obat Antituberkulosis Fdc Kategori 1 Di Provinsi Banten Dan Provinsi Jawa Barat’, Media Penelitian dan Pengembangan Kesehatan, 24(1), pp. 28–35. doi: 10.22435/mpk.v24i1.3484.28-35. Sukraningsih, Dwi Rahayu., Darmawati, S. and Wilson, W. (2014) ‘Perbedaan Hasil Pemeriksaan Basil Tahan Asam Metode Ziehl Neelsen dan GeneXpert’, pp. 7–28. Available at: http://repository.unimus.ac.id/1278/.

Depkes RI. 2009. Pedoman Nasional Penanggulangan Tuberkulosis. Jakarta: Gerdunas-TB.

Depkes RI. 2010. Petunjuk Teknis Penatalaksanaan Pasien TBMDR. Jakarta.

Kumar S, Ambree K, Sharma R, Sigh KP. Anti-tuberculosis drug induce hepatotxicity: a review. International Journal of Advance Biotechnology and Research. 2014; vol 5, issue 3, 423-437.13.