Test Of Bay Leaf Extract (Syzygium polyanthum) As An Antidiabetic Using Mouse Test Animals (Mus musculus)

Abstract

Diabetes mellitus is a cause of hyperglycemia. Diabetes mellitus is the most common cause of hyperglycemia, while other factors can also cause it. Diabetes mellitus causes sugar to accumulate in the blood, preventing it from entering cells. Bay leaves are woody plants that are often harvested for their leaves. Bay leaves have traditionally been used as a spice. There are many ways to use bay leaves as traditional medicine. Bay leaves have extraordinary therapeutic abilities and are commonly used in the treatment of hypertension and diabetes. Mice are commonly used as experimental animals in scientific research because of their short life cycle, large number of offspring per birth, high variation in traits, ease of handling, and the ability to detect anatomical and physiological features. The purpose of this study was to determine the decrease in antidiabetic in mice (Mus musculus) by administering bay leaf extract (Syzygium polyanthum) induced by glucose. The type of research used an experimental method (Quantitative Research) to test bay leaf extract (Syzygium polyanthum) as an antidiabetic drug in mice (Mus musculus). The results of this study found that giving bay leaf extract at a dose of 6 mg/20 g body weight, 20 mg/20 g body weight, and 33 mg/20 gs body weight can reduce blood glucose levels in mice for 7 days. This study found that bay leaf extract (Syzygium polyanthum) significantly reduced blood sugar levels in mice, with a value of (10.779<2.352.).